000 02066nab a2200301 a 4500
003 AR-ReUNN
005 20260702004756.0
008 260701s2023 ag |||||||||||||||||spa
100 1 _aSaglam, Mehmet
_9197153
700 1 _aKoseoglu, Serhat
_9197154
700 1 _aAral, Cuneyt Asm
_9199477
700 1 _aSavran, Levent
_9199478
700 1 _aPekbagriyanik, Tugba
_9197152
700 1 _aCetinkaya, Ayse
_9199479
245 1 0 _aIncreased levels of interleukin-33 in gingival crevicular fluids of patients with chronic periodontitis
264 1 _c2023
300 _a7 páginas
520 _aThe purpose of this clinical study is to comparatively investigate the interleukin-33 (IL-33) levels in gingival crevicular fluid (GCF), saliva and plasma of patients with periodontal disease as well as periodontally healthy subjects and the association between these levels and clinical parameters. GCF, saliva and plasma samples were collected from systemically healthy, non-smoker chronic periodontitis patients (CP group, n = 20), gingivitis patients (G group, n = 20) and periodontally healthy control groups (H group, n = 20). Full-mouth clinical periodontal parameters were also recorded. IL-33 levels were determined by ELISA. The total amount of GCF IL-33 was greater in the G and CP groups compared to the H group (p < 0.05). The GCF IL-33 concentration was significantly lower in the CP group than in the H and G groups (p < 0.001). Salivary or plasma IL-33 levels were similar in the study groups. The total amount of GCF IL-33 was positively correlated with the GI, PI and BOP (%) (p < 0.05). Considering the present findings, the increase in total amounts of GCF IL-33 may have a role in the pathogenesis of periodontal disease.
650 4 _aLiquido Crevicular Gingival
_9199480
650 4 _aInterleucina-33
_9199481
650 4 _aEnfermedades Periodontales
_910289
650 4 _aPlasma
_980296
650 4 _aSaliva
_912414
773 0 _tOdontology
_x1618-1247
_gv. 105 n. 2 (2017)
_w257190
942 _cART
035 _a(ODN)65695
001 266534
999 _c266534
_d266534
040 _aAR-ReUNN
_bspa
_cAR-ReUNN
_eaacr2