000			02290nab a2200289 a 4500
003			AR-ReUNN
005			20260702003057.0
008			260630s2006 ag |||||||||||||||||eng
041	0		_aeng
100	1		_aMorgan, Marjorie S. _9147550
700	1		_aMoore, Peter F. _9147551
700	1		_aStemmer, Betty L. _9147552
700	1		_aRapp, Christine M. _9147553
700	1		_aArlian, Larry G. _9147554
245	1	0	_aCharacterization of lymphocyte subtypes in scabietic skin lesions of naive and sensitized dogs / Larry G. Arlian ...[et al.].
264		1	_c2006
300			_a12 páginas
500			_aDisponible en caja 26 no 8 de INICNE
520			_aWe delineated the density of cells expressing CD4, CD8, CD21 and CD45RA antigens in the cellular infiltrates in the epidermis, dermis and follicular epithelium in scabietic skin lesions of naive hosts and sensitized hosts that expressed resistance to scabies infestation. No cells expressing CD21 (B- lymphocytes and follicular dendritic cells) were present in the epidermis and only a few were occasionally present in the dermis during both the first and second infestations. Naive T-cells (CD45RA +) and CD8 + cells (cytotoxic and suppressor T- lymphocytes) were present in varying densities in the infiltrates throughout the epidermis, dermis and follicular epithelium with no apparent differences in density and the rate of appearance between sensitizing and challenge infestations. CD4 + cells were abundant in fluctuating densities in the dermis, epidermis, and follicular epidermis during the sensitizing infestation and these cells became the dominant cell type early during the challenge infestation. The density of CD4 + cells in the infiltrate was much greater during the challenge than during the sensitization infestation. This population of CD4 + cells consisted of both T-helper/inducer cells and neutrophils and the large increase in their numbers during the challenge suggested they played a key role in the successful immune/inflammatory response that resulted in resistance to scabies infestation.
650		4	_aPerro _910161
650		4	_aLesiones _910073
650		4	_aRiñones _9119681
773	0		_tVeterinary Parasitology _gv. 4 (68) _w234688
942			_cART
035			_a(INICN)35977
001			234689
999			_c234689 _d234689
040			_aAR-ReUNN _bspa _cAR-ReUNN _eaacr2