02114nab a2200313 a 4500003000900000005001700009008004100026100002700067700002900094700002900123700002700152700003300179700002800212245010800240264000900348300001600357520114700373650004001520650002801560650003801588650001801626650001801644773005401662942000801716035001501724001000701739999001901746040003501765AR-ReUNN20260702004756.0260701s2023 ag |||||||||||||||||spa 1 aSaglam, Mehmet91971531 aKoseoglu, Serhat91971541 aAral, Cuneyt Asm91994771 aSavran, Levent91994781 aPekbagriyanik, Tugba91971521 aCetinkaya, Ayse919947910aIncreased levels of interleukin-33 in gingival crevicular fluids of patients with chronic periodontitis 1c2023 a7 páginas aThe purpose of this clinical study is to comparatively investigate the interleukin-33 (IL-33) levels in gingival crevicular fluid (GCF), saliva and plasma of patients with periodontal disease as well as periodontally healthy subjects and the association between these levels and clinical parameters. GCF, saliva and plasma samples were collected from systemically healthy, non-smoker chronic periodontitis patients (CP group, n = 20), gingivitis patients (G group, n = 20) and periodontally healthy control groups (H group, n = 20). Full-mouth clinical periodontal parameters were also recorded. IL-33 levels were determined by ELISA. The total amount of GCF IL-33 was greater in the G and CP groups compared to the H group (p < 0.05). The GCF IL-33 concentration was significantly lower in the CP group than in the H and G groups (p < 0.001). Salivary or plasma IL-33 levels were similar in the study groups. The total amount of GCF IL-33 was positively correlated with the GI, PI and BOP (%) (p < 0.05). Considering the present findings, the increase in total amounts of GCF IL-33 may have a role in the pathogenesis of periodontal disease. 4aLiquido Crevicular Gingival9199480 4aInterleucina-339199481 4aEnfermedades Periodontales910289 4aPlasma980296 4aSaliva9124140 tOdontologyx1618-1247gv. 105 n. 2 (2017)w257190 cART a(ODN)65695266534 c266534d266534 aAR-ReUNNbspacAR-ReUNNeaacr2